Search results for " beauty"
showing 10 items of 28 documents
Nuclear inclusions of pathogenic ataxin-1 induce oxidative stress and perturb the protein synthesis machinery
2020
Spinocerebellar ataxia type-1 (SCA1) is caused by an abnormally expanded polyglutamine (polyQ) tract in ataxin-1. These expansions are responsible for protein misfolding and self-assembly into intranuclear inclusion bodies (IIBs) that are somehow linked to neuronal death. However, owing to lack of a suitable cellular model, the downstream consequences of IIB formation are yet to be resolved. Here, we describe a nuclear protein aggregation model of pathogenic human ataxin-1 and characterize IIB effects. Using an inducible Sleeping Beauty transposon system, we overexpressed the ATXN1(Q82) gene in human mesenchymal stem cells that are resistant to the early cytotoxic effects caused by the expr…
"Table 1" of "Elliptic flow of electrons from beauty-hadron decays in Pb-Pb collisions at $\sqrt{s_{\rm NN}}$ = 5.02 TeV"
2021
$v_{2}$ of electrons from beauty hadron decays as a function of $p_{\rm T}$ in the centrality range 30-50% for $\sqrt{s_{\rm NN}}=5.02 {\rm~TeV}$
Bello e Idea nell’estetica del Seicento
2007
The Beautiful and The Idea in 17th-Century Aesthetics In his renowned lecture on the Idea, which he delivered at the Academy of Saint Luke in 1664, Giovan Pietro Bellori asserts the superiority of ideal beauty against the slavish imitation of reality and the unbridled freedom of the imagination. However, an equally important, albeit lesser known, contributor to the formulation of this classicist aesthetic theory is Giovan Battista Agucchi, author of a Treatise on Painting that appeared in fragmentary form in 1646. In this work, Agucchi identifes beauty as the truest and highest aim of painting; he attributes to the artist the power to contemplate the Idea, and confers a profound cognitive v…
The attractiveness of narcissists: Hard work or natural beauty?
2019
Are narcissists more attractive and perceived as such? In a preregistered multi-Study project, we aimed at gaining differentiated insights into this classic question, by considering agentic and ant...
Pomiędzy jawą a snem. Motyw piękna i przemocy w "Krystalicznej sieci" Mirko Kovača
2012
The narrator of Crystal Gates who is the protagonist of the novel too is making areconstruction of his youth and the artistic life in Belgrade of the 1960s. As he said, he has seen the past “in the lucid intervals” and dreams are really important in the story. They are usually connected with the real life and sometimes they are a kind of vision. The most important themes of the novel are beauty and violence. They are still related to each other, because they are two points of human life in general. The narrator is abudding writer, earning his living by trading in works of art and moving in artistic circle. On the other hand, he gets into touch with the exponents of new authorities (communis…
Prefazione al volume Corpi e identità : Donne dal Subcontinente indiano all’Italia di K. Carnà e S. Rossetti
2021
The preface to the book 'Bodies and Identities' highlights some of the themes addressed by the authors - K. Carnà and S. Rossetti. Carnà and S. Rossetti. Ignazia Bartholini highlights how the theme of body care and facial embellishments is declined in different practices oriented by the culture of origin of the women interviewed. Bangladeshi women, Indian, Pakistani and Sri Lankan women who let us in on some of their secrets of beauty" but, above all, they allow us to share stories to share stories closely linked to rites of passage in which care and beauty are not just ends in themselves, but constitute forms of entry into the native culture.
Tratamiento jurídico de una enfermedad social. Los trastornos de la conducta alimentaria (TCA)
2018
The boundless increase of people suffering from an Eating Disorder (ED), makes necessary to develop measures related to other factors, in order to overcome the ones characterized of being strictly sanitary. The disease has become a social and cultural phenomenon. The exaltation of the cult to the body, with the stereotype of the extreme thinness linked with beauty and success is causing that, particularly young people, try to achieve an image which, in many cases, can jeopardize their health, that is the reason why the rearrangement of values has become an objective of paramount importance. Therefore, the fight against this social illness requires legal actions in order to prevent it from g…
Sleeping Beauty transposon system – future trend in T-cell-based gene therapies?
2006
Evaluation of: Huang X, Wilber AC, Bao L et al.: Stable gene transfer and expression in human primary T cells by the Sleeping Beauty transposon system. Blood 107, 483–491 (2006). The Sleeping Beauty (SB) transposon system can mediate stable gene transfer and expression in primary human T cells. Optimal in vitro conditions for maximum gene transfer efficiencies have been developed with regard to further application of the SB transposon system in T cell based gene therapies. This raises the question of whether or not the SB transposon system is a convincing alternative for virus-mediated gene transfer based on the currently available data. Here, we will discuss controversial safety and effic…
RNA-based regulation of transposon expression
2015
Throughout the domains of life, transposon activity represents a serious threat to genome integrity and evolution has realized different molecular mechanisms that aim to inhibit the transposition of mobile DNA. Small noncoding RNAs that function as guides for Argonaute effector proteins represent a key feature of so-called RNA interference (RNAi) pathways and specialized RNAi pathways exist to repress transposon activity on the transcriptional and posttranscriptional level. Transposon transcription can be diminished by targeted DNA methylation or chromatin remodeling via repressive Histone modifications. Posttranscriptional transposon silencing bases on degradation of transposon transcripts…
Cosmetic Practices: The Intersection with Aesthetics and Medicine
2018
According to Shusterman, somaesthetics is as an aesthetic-ethical art of living, a practice devoted to living an attractively good life. So the aesthetic experience is not limited to art, but concerns also everyday life; consequently we can explain cosmetic practices (from make-up and hair-styling to plastic surgery) not only as making beauty, but also as feeling beauty, as a feeling better with oneself and with others. When beyond aesthetics purpose there is a functional purpose, cosmetic practices meet the medical science. This essay focuses on Somaesthetics in relation to high culture and popular culture. Firstly, some artistic practices are examined, which operate onto or into the body …